PJ LB

Sunday, August 29, 2010

Preparation Formula and Storage & Uses of Calamine Solution

How Calamine Solution is prepared ?
What is the formula involved & How it can be Stored ?


Calamine lotion :

Type of preparation: suspension containing indiffusible solids for external use,
with bentonite as suspending agent.


Formula:

Calamine : 15g (astringent)


Zinc oxide : 5g (astringent and protective)


Bentonite : 3g (suspending agent)


Sodium citrate : 0.5g (causes partial deflocculation of the calamine and transforms
the bentonite from a gel to sol. In its absence the suspension is much thicker
and very difficult to pour from the container).


liquefied phenol : 0.5ml (antimicrobial preservative)


Glycerol : 5.0ml


Purified water…q.s. 100ml.




Method of preparation:


- Dissolve sodium citrate in water.


- Triturate the calamine, zinc oxide and bentonite with a solution of sodium citrate.
   Add the liquefied phenol and glycerin.


- Make up the volume to required volume.


Storage:

Stored in well closed containers and in a cool place. Do not freeze.



Use :

Astringent and protective.

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