How Calamine Solution is prepared ?
What is the formula involved & How it can be Stored ?
Calamine lotion :
Type of preparation: suspension containing indiffusible solids for external use,
with bentonite as suspending agent.
Formula:
Calamine : 15g (astringent)
Zinc oxide : 5g (astringent and protective)
Bentonite : 3g (suspending agent)
Sodium citrate : 0.5g (causes partial deflocculation of the calamine and transforms
the bentonite from a gel to sol. In its absence the suspension is much thicker
and very difficult to pour from the container).
liquefied phenol : 0.5ml (antimicrobial preservative)
Glycerol : 5.0ml
Purified water…q.s. 100ml.
Method of preparation:
- Dissolve sodium citrate in water.
- Triturate the calamine, zinc oxide and bentonite with a solution of sodium citrate.
Add the liquefied phenol and glycerin.
- Make up the volume to required volume.
Storage:
Stored in well closed containers and in a cool place. Do not freeze.
Use :
Astringent and protective.
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