GPAT - PGCET - GATE Study Material related to Antidepressant Agents

GPAT  Study Material related to Antidepressant Agents
For Quick Reference

Antidepressant Agents :

- Tricyclic Antidepresssants (TCAs) - Asendin, Elavil, Pamelor



- MAO Inhibitors - Nardil, Parnate


   Lithium


- SSRI (Serotonin Uptake Inhibitors) - Wellbutrin, Prozac, Paxil
 
Side / Adverse Effects of  Antidepressant Agents :
 
-  CNS - depression, seizures from abrupt withdrawal



-  CV - All variations


-   Food reactions with MAO inhibitors- (wine, cheese, smoked meats)
     May result in Hypertensive Crisis


 - TCAs highly abused, overdose frequent

Toxicity of  Antidepressant Agents :

- Treat Benzodiazepine ODs. with Romazicon



- MAOI O.D.s- S/S usually after 12 hours- IV Sodium Bicarbonate, Oral Procardia


- TCAs - Alkalinization- IVs with Sodium Bicarbonate