PHARMACEUTICAL INORGANIC CHEMISTRY SYLLABUS FOR I YEAR B.PHARMACY STUDEENTS FOR THE YEAR 2009-10

PHARMACEUTICAL INORGANIC CHEMISTRY
SYLLABUS FOR I YEAR B.PHARMACY
STUDEENTS FOR THE YEAR 2009-10

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JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
ANANTAPUR.

PHARMACEUTICAL INORGANIC CHEMISTRY

UNIT- I
1.Classification of Inorganic Pharmaceuticals based on their applications and therapeutic uses.
2.Sources of impurities, quality control and test for purity
3.Qualitative tests for anion and cations
4.Limit tests for arsenic, heavy metals, lead, iron, chloride and sulphate.

Note:Definition, Preparation, principle behind Assays / Limit tests and Uses of the compounds mentioned in Unit II to Unit VII

UNIT - II
1.Electrolytes:
a.Sodium and potassium replenishers: Sodium chloride, compound sodium chloride
solution (Ringer solution), potassium chloride, ORS.

b.Calcium replenishers: Calcium gluconate, dibasic calcium phosphate, calcium
chloride.

2. Acid base regulators: Sodium bicarbonate, sodium lactate, sodium
citrate/potassium citrate, sodium acetate and ammonium chloride

3. Dialysis fluids: Haemodialysis fluids.

UNIT III
Gastro-intestinal agents.
1.Acidifiers and Antacids: Dilute hydrochloric acid, sodium acid phosphate, sodium bicarbonate, aluminium hydroxide gel, dried aluminium hydroxide gel, magnesium oxide (Magnesia), magnesium hydroxide mixture, magnesium trisilicate.

2.Adsorbents and related drugs: Light kaolin, heavy kaolin and activated charcoal.

3.Laxatives: Magnesium sulphate, sodium phosphate.

UNIT -IV
1) Mineral Nutrients / Supplements
(a) Haematinics – Ferrous sulphate, ferrous fumarate, ferrous gluconate,
ferric ammonium citrate, iron and dextrose injection.

(b)Halogens: Iodine, Iodides.

2) Pharmaceutical aids
(a) Excipients: Dicalcium phosphate, magnesium stearate, talc and calcium
carbonate (Precipitated chalk).

(b) Suspending agents: Bentonite, colloidal silica.
(c) Colorants: Titanium oxide, Ferric oxide

UNIT- V

(a) Expectorants: Ammonium chloride, potassium iodide.
(b) Emetics: Potassium antimony tartarate, copper sulphate.
(c) Antidotes: Sodium thiosulphate, sodium nitrite.



UNIT -VI
Topical agents:
1)Astringents: Zinc sulphate, calcium hydroxide, Bismuth sub carbonate.

2)Topical protectants: Zinc oxide, calamine, zinc stearate, talc, titanium-dioxide, heavy kaolin and light kaolin (only uses).

3)Silicone polymers: Activated dimethicone.

4)Anti-infectives: Hydrogen peroxide solution, potassium permanganate, silver nitrate (silver protein), iodine, (solutions of iodine, povidone iodine),
boric acid, zinc undecylenate, mercury compounds (yellow mercuric chloride).


UNIT- VII
Dental products:
1)Fluorides: Sodium fluoride, sodium monofluorophosphate and stannous fluoride.
2)Oral antiseptics and astringents: Hydrogen peroxide, magnesium peroxide, zinc peroxide and mouth washes.

3)Dentifrices: Calcium carbonate, dibasic calcium phosphate, calcium phosphate, sodium metaphosphate and strontium chloride.

4)Cements & fillers : Zinc oxide (uses only).

UNIT-VIII
Miscellaneous Medicinal Agents
a) Antineoplastics : Cisplatin
b) Antidepressants : Lithium carbonate
c) Diagnostic agents : Barium sulphate
d) Surgical aids : Plaster of Paris
e) Antirheumatic agents : Sodium aurothiomalate
f) Internal parasiticid : Sodium antimony gluconate
g) Anti thyroid agents : Potassium perchlorate

TEXT BOOKS

1. Pharmaceutical Inorganic Chemistry by Madan-S.Chand
2. Inorganic Medical and Pharmaceutical Chemistry, J.H Block, E.Roche, T.O Soine and C.O. Wilson, Lea &
Febiger Philadelphia PA.

REFERENCES
1.Practical pharmaceutical chemistry, Part-I, A.H.Beckett and J.B.Stenlake, The Athtone press, University of London, London.

2.Inorganic chemistry, Gary L.Miessler and Donald A.Tarr,3/e, Pearson education,
New Delhi

3.Inorganic pharmaceutical chemistry, P. Gundu Rao, Vallabh Prakashan, Delhi.
4.Advanced Inorganic Chemistry, G.D.Tuli, Satya prakash
5.Modern inoraganic chemistry, Jolly
6.Indian Pharmacopoeia 1996, 2006.